Antifibrotic and anthelminthic effect of casticin on Schistosoma mansoni-infected BALB/c mice
نویسندگان
چکیده
منابع مشابه
Effect of Curcuma longa or parziquantel on Schistosoma mansoni infected mice liver--histological and histochemical study.
Effect of drug praziquantel (PZQ) and C. longa extract on S. mansoni infected mice is reported. The level of glycogen, alkaline and acid phosphatases (ALP and ACP respectively), and body weight, liver weight and liver weight/body weight ratio were studied in mice infected with S. mansoni. ALP level was increased after infection. C. longa treated mice showed marked reduction in ALP level more th...
متن کاملAnaphylaxis with Schistosoma mansoni extracts in normal and infected mice.
M e t h o d s genera l ly u t i l ized for s t u d i e s o n a n a p h y l a x i s t o p r o t e i n a n t i g e n s s u c h a s d e t e r m i n a t i o n of h i s t a m i n e re l ease t o t h e b lood , h e m o c o n c e n t r a t i o n , h i s t a m i n e r e l ea se f r o m p e r i t o n e a l m a s t cells a n d pas s ive c u t a n e o u s a n a p h y l a x i s (PCA) w e r e u s e d t o i ...
متن کاملBrain schistosomiasis in mice experimentally infected with Schistosoma mansoni.
Introduction Human neuroschistosomiasis has been reported in the literature, but the possibility of modeling neuroschistosomiasis in mice is controversial. Methods In two research laboratories in Brazil that maintain the Schistosoma mansoni life cycle in rodents, two mice developed signs of brain disease (hemiplegia and spinning), and both were autopsied. Results S. mansoni eggs, both with and ...
متن کاملPassive avoidance response in mice infected with Schistosoma mansoni.
Schistosomiasis is a parasitic disease of humans and rodents affecting more than 200 million people worldwide. Following the onset of infection, the worms induce granulomas around schistosome eggs in the liver, intestine and central nervous system (both brain and spinal cord), which are likely to cause changes in cognitive functions. In the present study, CD-1 female mice were percutaneously in...
متن کاملEffect of Treatment with Antifibrotic Drugs in Combination with PZQ in Immunized Schistosoma mansoni Infected Murine Model
The main problem in schistosomal hepatic morbidity is fibrosis and extensive scarring induced by living eggs. In this study, we tried to study the effect of treatment using antihelminthic drug (PZQ) and/or antifibrotic drugs (PTX and silymarin) in combination with immunization. The parasitological parameters, the dynamics of serum-specific immunoglobulins and splenic cytokines associated with c...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Microbiology, Immunology and Infection
سال: 2021
ISSN: 1684-1182
DOI: 10.1016/j.jmii.2021.03.017